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You may also need to monitor your blood pressure at home. This website is intended for use by US patients. Hemoglobin is a protein thats found inside your red blood cells. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Learn about uses, cost, how it works, and more. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. All rights reserved. Venofer injection contains iron sucrose, a form of the mineral iron. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. For example: Say you weigh 105 pounds (about 48 kilograms). An iron infusion is a way to increase the body's iron levels quickly. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. They have been a god send. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Review our medical disclaimer. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. If you have questions about side effects, call your doctor. However, consuming large amounts of alcohol can actually cause anemia in some people. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Once inside your body, ferric carboxymaltose releases iron into your system. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Tell your doctor if you are pregnant or plan to become pregnant. No, you wont need to take iron pills while youre using Injectafer. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. All of the people took iron by mouth for 2 weeks. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Some people only need one treatment course of Injectafer. However, be sure to take the dosage your doctor prescribes for you. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. endobj How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Should I avoid certain foods while taking Venofer Vial? I was surprised too but the Dr said it definitely sounds like a reaction. Injectafer can cause mild or serious side effects. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). But so far I feel better than before the infusion. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. No, you most likely wont take Injectafer long term. If you notice any changes to your normal blood pressure, call your doctor right away. Any long-term side effects/dangers from iron infusions? Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Follow your doctor's directions carefully. One of the most commonly used tests to monitor IDA is the hemoglobin test. People in the study received treatment with either Injectafer or Venofer. Hemoglobin is a protein thats found in your RBCs. Following an LSD trip, users may experience a sort of 'comedown.'. This information is not specific medical advice and does not replace information you receive from the healthcare provider. In the second group, some people switched from taking iron by mouth to taking Injectafer. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. As with most drugs, some people can have an allergic reaction after taking Injectafer. Call your doctor for medical advice about side effects. % This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. %PDF-1.3 Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. It is given into a vein for a period of time. People with IDA have low blood levels of hemoglobin. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. cough. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. What are the side effects of Venofer? administered at your doctors office or an infusion center. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Examples of these side effects include dizziness and nausea. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Which tests can diagnose iron deficiency anemia? This document does not contain all possible drug interactions. <> It is usually given slowly over 2 to 5 minutes or as directed by your doctor. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. In Canada - Call your doctor for medical advice about side effects. Keep all regular medical and laboratory appointments. Learn more about these, as well as the symptoms, diagnosis, and treatments. Mental healthdisorders like depression may requireantidepressantsto treat. They can tell you about other medications that may work well for you. Copyright 1996-2023 Cerner Multum, Inc. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Injectafer and Venofer can cause very similar side effects, but some different ones as well. But keep in mind that in this study, delayed allergic reaction only occurred in one person. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. WebMD provides common contraindications for Venofer Vial. Have blood work checked as you have been told by the doctor. * This is a partial list of mild side effects from Injectafer. Side effectswill last a very long time if the cause of them is not resolved. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. weakness. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. The following information is provided for clinicians and other healthcare professionals. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Venofer Side Effects. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Terminal half-life ranges from 7 to 12 hours. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. All rights reserved. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Below are examples of these side effects. US residents can call their local poison control center at 1-800-222-1222. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Here's some detail on certain side effects this drug may cause. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Potential injection site discoloration has happened. Their medical staff can help you set up another time to receive your Injectafer dose. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). You should always consult your doctor or another healthcare professional before taking any medication. We comply with the HONcode standard for trustworthy health information. Properly discard this product when it is expired or no longer needed. There may be drug take-back programs in your area. Version: 7.01. 4 0 obj But you dont necessarily need to eat these foods unless your doctor tells you to do so. You may report side effects to FDA at 1-800-FDA-1088. Brand-name medications usually cost more than generics. Theyll recommend how to manage your condition. However, diarrhea it isnt very common in people using Injectafer. It may also cause nervousness, restlessness, and difficulty sleeping in some people. After the infusion, you can drive yourself home and return to your usual activities. Others last much longer (even a lifetime), which can be quite traumatizing to people. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. intense abdominal pain. Venofer pregnancy and breastfeeding warnings. 2023 Medicine.com All rights reserved. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Serious side effects should be reported to a physician and/or PharmD for medical advice. Medically reviewed by Sanjai Sinha, MD. There are currently no generic forms of either drug. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Injectafer is available only as a brand-name medication. Things to remember when you fill your prescription. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Depending on your anemia symptoms, your weight changes may be different than those described here. Tell your doctor about the allergy and what signs you had. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Iron sucrose can also be mixed in a. During pregnancy, this medication should be used only when clearly needed. Details. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. But you kidneys need iron in order to make EPO. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. The benefit of treating your condition during pregnancy may outweigh any risks. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Some products that may interact with this drug include: vitamin products, other iron-containing products. Discuss the risks and benefits with your doctor. What is the latest research on the form of cancer Jimmy Carter has? Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Yes, in some cases it may. These changes could help improve your anemia on a long-term basis. This website is intended for use by US healthcare professionals only. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Drug interactions may change how your medications work or increase your risk for serious side effects. This is only a brief summary of general information about this medicine. Feraheme also comes as a liquid thats given by IV infusion. This is not a complete list of possible side effects. upper respiratory infection. Pain in your limbs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Many patients with kidney disease cannot get enough iron from food and require injections. These people may lose weight as their anemia improves because theyre more active. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. If youre interested in finding an alternative to Injectafer, talk with your doctor. Allergic reactions typically occur the first time your body is exposed to a drug. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. It belongs to a class of medications called iron replacement products. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. 2. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. As a result, you may not make as much EPO as usual. And these two doses need to be separated by at least 7 days. Your doctor will be able to see how Venofer is working by reviewing your blood tests. You may need extra iron because of blood loss during kidney dialysis. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Ask your doctor or healthcare provider if Venofer is the right choice for you. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. It's a more immediate treatment than supplements or dietary changes. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. (For more information on Venofer, see the Injectafer vs. Venofer section above). You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. . Most people do not know how long theirside effectswill last until they go through them. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. 3 0 obj Consult your doctor before breast-feeding. Does Venofer Vial interact with other drugs you are taking? (A class of medications describes a group of drugs that work in the same way.). As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes muscle pain. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Cancer patients who have anemia and are taking an ESA. Learn how to store and discard medical supplies safely. The following information describes dosages that are commonly used or recommended. (And Injectafer is used to treat IDA.) Answer by DrLact: About Venofer usage in lactation. Sharing this information can help you avoid potential interactions. There have also been reports of serious allergic reactions to Venofer. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Before taking Injectafer, talk with your doctor about your health history. Low iron saturation, or iron deficiency, has various possible causes. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. A shortage of iron can cause health problems. These effects typically last between 7 and 11 hours. (IV iron is absorbed by the body more rapidly than oral iron.) Many people using this medication do not have serious side effects. Iron infusion benefits. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Low blood pressure. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. The following lists contain some of the key side effects that may occur while taking Injectafer. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Call your doctor for instructions if you miss an appointment for your Venofer injection. If your symptoms or health problems do not get better or if they become worse, call your doctor. People with IDA have low blood levels of hemoglobin. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Last updated on Feb 20, 2023. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Understanding what thoseside effectsare can lead to a strategy to prevent them. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. What is Venofer? Someside effectsare temporary or last as long as the person continues takingprescription medicine. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Side effectsare uncomfortable reactions to medications or drugs. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. This is not a list of all drugs or health problems that interact with this medicine. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Venofer is not for treating other forms of anemia not caused by iron deficiency. Cardiovascular health: Insomnia linked to greater risk of heart attack. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose.