A case of Pityriasis rosea is presented in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine. 2021;185(2):e34. Unable to load your collection due to an error, Unable to load your delegates due to an error. Federal government websites often end in .gov or .mil. Published by Elsevier Inc. Pityriasis rosea. eCollection 2022. Written informed consent was obtained from the individual(s) for the publication of any potentially identifiable images or data included in this article. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. J Eur Acad Dermatol Venereol. While it can spread all over the entire body, PR usually favors the trunk, says Christina Lam, an assistant professor of dermatology at Boston University School of Medicine and dermatologist at Boston Medical Center. doi: 10.1111/bjd.20143. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). and transmitted securely. Epub 2022 Jun 14. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature JAAD Int. JAAD Int. 2021 Sep;60(9):1150-1151.doi: 10.1111/ijd.15700. COVID-19; SARS-CoV-2; pityriasis rosea; vaccination. Accessibility Women are 50% more likely to develop pityriasis rosea. Keywords: Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. It said blood spots under the skin might also be present, either as spots or dots or on larger areas. Pityriasis Rosea Induced by COVID-19 Vaccination - PubMed The clinics of HHV-6 infection in COVID-19 pandemic: Pityriasis rosea and Kawasaki disease. Of the reported cases, 96.7% were secondary to the Pfizer vaccine, with only 1 reported . Clin Exp Dermatol 2010;35:3004. official website and that any information you provide is encrypted Pityriasis Rosea Induced by COVID preview & related info | Mendeley sharing sensitive information, make sure youre on a federal These conditions lasted 8.6 days on average. Epub 2022 Feb 9. Moreover, central dusky-red erythematous was observed on some plaques (Figure 2A). Learning points: Lasers Med Sci. PMC Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. This site needs JavaScript to work properly. Bookshelf Influenza viruses and vaccines have triggered pityriasis rosea in some cases.". Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. Would you like email updates of new search results? "And it has a particular [dermatomal] distribution because it's along a nerve," which also presents as fluid-filled blisters, rather than lesions. JAAD Int. government site. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. doi: 10.1111/jdv.12942, 13. (2019) 34:185764. (b) Patient 1: Closeup of a plaque. (2016) 55:e33843. (A) Dermoscopic features: dotted and linear vessels forming a network on a yellowish background with some whitish peripheral scales (original magnification x20). This patch is the herald or mother patch. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Before Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. doi: 10.1159/000517971. Your Random Rash Could Be Pityriasis Rosea | Allure Australas J Dermatol. Unauthorized use of these marks is strictly prohibited. official website and that any information you provide is encrypted Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. You may be at risk of developing an allergic reaction on your skin. Treatment was initiated with systemic corticosteroid therapy - hydrocortisone hemisuccinate 200 mg/day for 7 days, and loratadine 10 mg 2 times a day. 94 PDF Pityriasis rosea and pityriasis rosea-like eruptions: How to distinguish them? Authors Jordan E Buckley 1 , Laura N Landis 2 , Ronald P Rapini 1 Affiliations (a) haematoxylineosin, original magnification 10. While you don't need to treat the rash, some patients ask for treatment to take care of the following. Dermatol Ther. COVID-19 has been reported as one such viral trigger for PR. However, the studies dont conclusively prove that COVID-19 causes pityriasis rosea. Atypical pityriasis rosea associated with mRNA COVID-19 vaccine. If you have a very itchy rash, your healthcare provider may prescribe the following to help relieve your symptoms: There are several over-the-counter products or home remedies that can help stop your rash from itching. Br J Dermatol. retailers. Epub 2021 Apr 26. Epub 2022 Jan 5. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). PR is a rare cutaneous reaction after mRNA vaccination against SARS-CoV-2. and transmitted securely. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. The patient developed papulovesicular lesions in the crease lines of the trunk and extremities, four days after inoculation with a recombinant coronavirus vaccine (Covishield, India). (2021) 85:4655. NCI CPTC Antibody Characterization Program, Ritchie H., Mathieu E., Rodes-Guirao L., et al. eCollection 2021. The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. Vaccinations have been identified to rarely cause several cutaneous reactions. Int J Infect Dis. HHS Vulnerability Disclosure, Help Develop a large patch on your skin. "In studies, between 2 and 3 percent of people develop the disease again. J Med Virol. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. This site needs JavaScript to work properly. Bookshelf doi: 10.1111/j.0022-202X.2005.23719.x. Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. Cutaneous Eruptions in the Course of COVID-19 Among Geriatric Patients in a Nursing Home in Poland. JAAD Case Rep. (2018) 4:8001. Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of COVID19. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. Patient concerns: However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. This rash is thought to be caused by a virus. (d) Patient 2: Closeup of plaques, with the hyperpigmented centre and trailing scale. Rybak-d'Obyrn J, Placek W, Owczarczyk-Saczonek A, Derkaczew M, Joniec E, Hofman R, Stompr M. Clin Cosmet Investig Dermatol. The site is secure. The authors of one 2014 case report of a 71-year-old man who suffered from pityriasis rosea one month after receiving an influenza vaccine concluded that "altered immunity" could result in reactivation of HHV-6 and/or HHV-7 which may have triggered an atypical presentation of PR. Clinical aspect of the lesions after 7days of treatment. headache.2 Several cutaneous adverse events after anti-COVID-19 vaccination are described in the literature, such as delayed large local reaction, urticaria, morbilliform eruptions, herpes zoster, "COVID arm," pityriasis rosea.3,4,5 Here, we report a case of a patient who presented with herpes zoster ophthalmicus (HZO) after the third dose 2021;35(9):e546e548. 2023 Cond Nast. With COVID-19 vaccines being authorized for emergency use, monitoring for potential adverse effects (e.g., cutaneous reactions) is necessary. "However, it's possible to develop the rash more than once," she says. Following the national COVID-19 vaccination guidelines, she received a shot of ChAdOx1 nCoV-19 (AZD1222) vaccine before the therapy. These findings were consistent with a diagnosis of PR-like eruption. COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine We present two cases of COVID-19 vaccine-induced pityriasis rosea. However, in cases of atypical PR, it may present with erythema multiforme-like lesions and purpura (5). PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. Khalili M, Abtahi-Naeini B, Rastegarnasab F, Afshar K. Clin Case Rep. 2022 Jul 19;10(7):e6096. Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. See this image and copyright information in PMC. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. Would you like email updates of new search results? FOIA The available COVID-19 vaccines entail different levels of risk for skin reactions. The https:// ensures that you are connecting to the Rashes Could Be 'Key Sign' Of Covid-19. Here's What They Look Like Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. 2023 Feb 9;11(2):397. doi: 10.3390/vaccines11020397. eCollection 2022. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A Please enable it to take advantage of the complete set of features! 2021 Aug;185(2):e34. Disclaimer. Herein, we are reporting a unique. The .gov means its official. User Agreement and Privacy Policy and Cookie Statement and Central dusky-red erythematous on some plaques (A); almost all lesions fading with associated post-inflammatory hyperpigmentation after treatment (B). Histopathologic features: (B) microscopic image at a low power field showing psoriasiform epidermal hyperplasia, perivascular infiltration, and interface dermatitis (hematoxylin-eosin; scale bar represents 100 m); (C) microscopic image at a high power field showing focal spongiotic dermatitis, interface dermatitis, and perivascular infiltration of lymphocytes and eosinophils (hematoxylin-eosin; scale bar represents 40 m). (Unfortunately, I scratched my rash until it bled, so my hyperpigmentation may linger.). Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. HHS Vulnerability Disclosure, Help See your skin clear. (a) Pityriasis rosea (chest, flank, and axilla); (b) pityriasis rosea (back). 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. An official website of the United States government. Epub 2020 Jun 5. . J Eur Acad Dermatol Venereol. Some people see the rash disappear within 6 to 8 weeks, but it can take 5 months or longer for the skin to clear. eCollection 2022 Jul. If you have pityriasis rosea, its unlikely that youll get it again. Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. doi: 10.1111/jdv.17342. However, several adverse effects of COVID-19 vaccination have been identified. It is usually seen in children, adolescents, and young adults. In: Kelly A, Taylor SC, Lim HW, et al., eds. eCollection 2022 Feb. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. Get useful, helpful and relevant health + wellness information. Med Clin (Barc). Rashes can be a better sign of having Covid-19 than fever or - mirror The rash itself usually doesnt blister or bleed, but in many cases, the skin may peel. doi: 10.1097/MD.0000000000029823. Parakeratosis with minimal acanthosis and spongiosis of the epidermis. See this image and copyright information in PMC. Moreover, while dermoscopy may facilitate the diagnosis of PR, its utility for atypical PR or PR-like lesions is still limited. Clinical findings of pityriasis rosealike, Clinical findings of pityriasis rosealike eruption in the patients. Another skin condition identified in the study were "vesicular eruptions" seen in 9 per cent of cases. At first, I thought it was a mosquito bite. . No one knows what causes pityriasis rosea, though healthcare experts think a virus might be responsible. (2021) p. e15040. Contact your healthcare provider as soon as you notice a rash. A case of Herpes Zoster Ophtalmicus after third dose of Comirnaty If you need help purchasing a product directly from Allure, go to our FAQ. Proc (Bayl Univ Med Cent). It looked like one, and it certainly itched like one but then more came. However, if you scratch your patches, you may break your skin, leading to an infection that can cause pain. government site. Histopathologic examination revealed epidermal focal spongiosis, interface dermatitis with necrotic keratinocytes, perivascular lymphocytic infiltration, and few eosinophilic infiltrations in the superficial dermis (Figures 3B,C). [Epub ahead of print]. "Other treatments including phototherapy or oral medications can be considered for extensive or persistent cases, [and] some small case studies support the use of oral antivirals like acyclovir or oral anti-inflammatory antibiotics erythromycin," King explains. Pityriasis Rosea as a Possible Complication of Vaccination Against COVID-19. Br J Dermatol 2020; 183: 431442. Please enable it to take advantage of the complete set of features! Epub 2020 Jun 29. -, Neoh CY, Tan AW, Mohamed K, et al. The most commonly inoculated vaccines include those against smallpox, followed by tuberculosis, poliomyelitis, influenza, and human papillomavirus virus (12, 13). Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. doi: 10.1016/j.jaad.2021.03.092, 15. The condition is more prevalent in spring and fall. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. Epub 2022 Jun 21. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. Pityriasis rosea: Diagnosis and treatment - American Academy of Dermatology Some patients may have a cold before the rash. (2021) 93:18501. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.".